OECD 496 + OECD 435: the only 100% animal free in vitro tests for your testing strategies
Our OECD 496 and 435 tests are the only macromolecular, 100% animal-free in vitro tests that can be used in both a top-down and bottom-up strategy. PETA Approved Non-Animal Approaches to Skin and Eye Testing Ocular Irritection OECD 496 Ocular Irritection OECD 496 can be used as the first and only step in both integrated […]
Irritection® protocols can be performed with any plate reader
You don’t have one of the plate readers recommended for the use of Dermal & Ocular Irritection tests? No problem, if your plate reader has405 nm and 450 nm filters, you’ll be able to collect raw optical density (OD) data and then use our Irritection Analyticssoftware to perform data analysis and create a standard Irritection […]
The reason why the OECD 496 Ocular Irritection® protocol is better than the classical one for surfactant analysis
Many of our customers prefer to use the classical Ocular Irritection® protocol to evaluate the irritant potential of their surfactants for GHS and CLP classification. We at INT.E.G.RA., as European Training Center and partners of InVitro International, recommend the use of the OECD protocol, Test Guideline OECD 496, because of its greater accuracy. New studies […]
Speed, ease, animal free, grading capability: the advantages of Corrositex®
Only Corrositex® is able to classify the three GHS corrosive subcategories 1A, 1B and 1C TG OECD 431 only allows discrimination between Sub-cat. 1A from those 1B and 1C. TG OECD 430 is unable to discern between any subcategories. Only Corrositex® OECD 435, among all alternative in vitro methods OECD adopted, is able to identify […]
Speed, ease of use, animal free: the advantages of Ocular Irritection®
100% animal free TG OECD 492 uses a RhCE tissue model based on a human cell culture.TG OECD 491 uses a rabbit corneal cell line.TG OECD 437 and 438 make use of tissues from slaughterhouses.TG OECD 460 uses kidney cells. Only Ocular Irritection® TG OECD 496 uses a completely acellular and 100% animal free macromolecular […]
H3i 2021 – Declassify the hazard of your product with Corrositex®
In our first presence at H3i, in partnership with Flashpoint srl, we want to make sure your products aren’t labeled as corrosive when they shouldn’t be. Giveyour products aless hazardous classification in full compliance with current legislation with Corrositex® OECD 435, the only 100% animal freeskin corrosion test. Come and visit us at H3i 2021, […]
SCCS XI: OI® is the only 100% animal free OECD Test Guideline
100% in chemico & animal free As mentioned in the recent SCCS XI, the 11th revision of the “Guidance Notes for the Testing of Cosmetic Ingredients and the Evaluation of their Safety”, in paragraph 3–4.6, when talking about New Approach Methodologies (NAMs) for serious eye damage and eye irritation: TG OECD 492 uses a RhCE […]
Validating alternative methods
Welcome to the fourth episode of In Vitro Focus, a series of in-depth articles written by our technical staff to bring you to the heart of the world of cruelty-free testing. Together we’ll discover all the best practices, latest news, and key players in the industry that is striving to make animal testing a thing […]
Alternatives to animal testing
Welcome to the second episode of In Vitro Focus, a series of in-depth articles written by our technical staff to bring you to the heart of the world of cruelty-free testing. Together we’ll discover all the best practices, latest news, and key players in the industry that is striving to make animal testing a thing […]
The 3 Rs today
Welcome to the first episode of In Vitro Focus, a series of in-depth articles written by our technical staff to bring you to the heart of the world of cruelty-free testing. Together we’ll discover all the best practices, latest news, and key players in the industry that is striving to make animal testing a thing […]
