Only Corrositex® is able to classify the three GHS corrosive subcategories 1A, 1B and 1C
TG OECD 431 only allows discrimination between Sub-cat. 1A from those 1B and 1C.
TG OECD 430 is unable to discern between any subcategories.
Only Corrositex® OECD 435, among all alternative in vitro methods OECD adopted, is able to identify and classify the Cat.1 sub-category of the test substance.
Corrositex® is completely animal free
TG OECD 431 is based on the use of reconstituted human skin.
TG OECD 430 is based on isolated rat skin.
Corrositex® OECD 435 uses an artificial membrane designed to respond to corrosive chemicals in a manner similar to animal skin in situ.
OECD TG 435, page 2
