{"id":3342,"date":"2020-03-05T13:20:13","date_gmt":"2020-03-05T13:20:13","guid":{"rendered":"https:\/\/www.integracosmetics.com\/2020\/11\/27\/ocular-irritection-becomes-oi-oecd-496\/"},"modified":"2020-11-27T13:50:25","modified_gmt":"2020-11-27T13:50:25","slug":"ocular-irritection-becomes-oi-oecd-496","status":"publish","type":"post","link":"https:\/\/www.integracosmetics.com\/en\/2020\/03\/05\/ocular-irritection-becomes-oi-oecd-496\/","title":{"rendered":"Ocular Irritection\u00ae becomes OI\u00ae OECD 496"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3342\" class=\"elementor elementor-3342 elementor-772\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e549c71 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e549c71\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8d796b3\" data-id=\"8d796b3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f23dfc elementor-widget elementor-widget-text-editor\" data-id=\"1f23dfc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As co-owner for Europe of InVitro International, INT.E.G.RA. has taken over the years the legislative procedure for the acceptance of their in vitro methods in the European Union.<\/p>\n<p>This is why we are pleased to announce that<strong> Ocular Irritection\u00ae<\/strong> <strong>has been adopted by the OECD<\/strong> and is available for immediate global use according to its <a href=\"https:\/\/www.oecd-ilibrary.org\/environment\/test-no-496-in-vitro-macromolecular-test-method-for-identifying-chemicals-inducing-serious-eye-damage-and-chemicals-not-requiring-classification-for-eye-irritation-or-serious-eye-damage_970e5cd9-en;jsessionid=klS_QrM8zRsT_cBUnA2EvSzp.ip-10-240-5-121\" target=\"_blank\" rel=\"noopener\">Test Guideline (TG 496)<\/a>.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c86398c elementor-widget elementor-widget-heading\" data-id=\"c86398c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">OI\u00ae is the first OECD Test Guideline 100% a-cellular, animal &amp; cruelty free, and the first adopted TG presented by Italy.<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d74b1ad elementor-widget elementor-widget-image\" data-id=\"d74b1ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1536\" height=\"784\" src=\"https:\/\/www.integracosmetics.com\/wp-content\/uploads\/2019\/11\/Slide-for-website-1.jpg\" class=\"attachment-full size-full wp-image-1079\" alt=\"Ocular Irritection OECD 496 INTEGRA\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-138aafb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"138aafb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-f3533d0\" data-id=\"f3533d0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ee6c27b elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"ee6c27b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user-clock\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8090a18 elementor-widget elementor-widget-heading\" data-id=\"8090a18\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Results in 24H<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-b6ee102\" data-id=\"b6ee102\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-05b5e67 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"05b5e67\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-globe-americas\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d507b8 elementor-widget elementor-widget-heading\" data-id=\"3d507b8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Globally Accepted<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-920e93a\" data-id=\"920e93a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9644680 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"9644680\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"far fa-smile\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-211eac7 elementor-widget elementor-widget-heading\" data-id=\"211eac7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Easy to use<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-c74512c\" data-id=\"c74512c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e1e594b elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"e1e594b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-tint-slash\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-799b69d elementor-widget elementor-widget-heading\" data-id=\"799b69d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">No biology lab needed<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-44bdebb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"44bdebb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-033dd97\" data-id=\"033dd97\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e33b755 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"e33b755\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"far fa-eye-slash\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2277406 elementor-widget elementor-widget-heading\" data-id=\"2277406\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">No cell culture required<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-d38dc36\" data-id=\"d38dc36\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-461a254 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"461a254\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"far fa-clock\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9f3470e elementor-widget elementor-widget-heading\" data-id=\"9f3470e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Long shelf life<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-ef7fce7\" data-id=\"ef7fce7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b705afc elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"b705afc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"far fa-thumbs-up\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d15330 elementor-widget elementor-widget-heading\" data-id=\"1d15330\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Recommended by the OECD as a first test for both Bottom-Up and Top-Down strategy<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-4a7fd02\" data-id=\"4a7fd02\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-92a5554 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"92a5554\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-trophy\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-72dbc91 elementor-widget elementor-widget-heading\" data-id=\"72dbc91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">First OECD 100% chemical test<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8570876 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8570876\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60f57ca\" data-id=\"60f57ca\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5d68a7b elementor-widget elementor-widget-heading\" data-id=\"5d68a7b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">The path<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-69a9078 elementor-widget elementor-widget-text-editor\" data-id=\"69a9078\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This adoption culminates in an eleven-year effort with the OECD, the world&#8217;s first regulatory body for in vitro testing methods. Its 36 member countries, including the United States, account for about <strong>80% of world trade<\/strong>.<\/p>\n<p><strong>OI\u00ae<\/strong> is part of the <a href=\"https:\/\/www.integracosmetics.com\/en\/invitro-international\/irritection\/\" target=\"_blank\" rel=\"noopener\">Irritection\u00ae Assay System<\/a> together with <strong>Irritection\u00ae Dermal<\/strong>, which tests skin irritation.<\/p>\n<p>&#8220;<em>The adoption by the OECD of our eye irritation method represents for us, and for all those who care about the development of alternative animal-free tests, a source of great pride and pride, also because it is the first in vitro test presented by Italy to be adopted by the OECD. We presented the method 11 years ago, the process was long but this is the time required for adoption.<\/em><br \/>\n<em>OED 496 is the only Test Guideline completely in chemistry, without the need for cell biology or culture laboratories and will represent a great alternative, faster and more effective, to traditional testing methods<\/em>&#8220;.<\/p>\n<p>Says Davide Facchini, president and founder INT.E.G.RA.<\/p>\n<p>IVRO&#8217;s CEO, W. Richard Ulmer, also commented on the new status of Ocular Irritection\u00ae and its subsequent global acceptance: &#8220;<em>It has been a long but very rewarding process to achieve final adoption by the OECD. In 1985, IVRO pioneered 100% cruelty-free testing methods, when there was not even a specific regulatory body that set standards or approved testing methods worldwide. Now, 35 years later, the adoption of the OECD represents the highest level of scientific review for any non-animal test method<\/em>&#8220;.<\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96c6873 elementor-widget elementor-widget-heading\" data-id=\"96c6873\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.integracosmetics.com\/oecd496\/\">Discover OI\u00ae 496<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bf2d641 elementor-widget elementor-widget-heading\" data-id=\"bf2d641\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.oecd-ilibrary.org\/docserver\/970e5cd9-en.pdf?expires=1583415898&#038;id=id&#038;accname=guest&#038;checksum=6028FC1F5CF871D86EB2E91452CAD893\">Read the TG<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>As co-owner for Europe of InVitro International, INT.E.G.RA. has taken over the years the legislative procedure for the acceptance of their in vitro methods in the European Union. This is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1079,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","footnotes":"","_ppma_block_editor_authors":""},"categories":[25],"tags":[],"ppma_author":[39],"class_list":["post-3342","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ocular Irritection\u00ae becomes OI\u00ae OECD 496 - INT.E.G.RA.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.integracosmetics.com\/en\/2020\/03\/05\/ocular-irritection-becomes-oi-oecd-496\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ocular Irritection\u00ae becomes OI\u00ae OECD 496 - INT.E.G.RA.\" \/>\n<meta property=\"og:description\" content=\"As co-owner for Europe of InVitro International, INT.E.G.RA. has taken over the years the legislative procedure for the acceptance of their in vitro methods in the European Union. 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